The Merrit Alloantigenic System of Human B Lymphocytes: Evidence for Thirteen Possible Factors including one Six-Member Segregant Series
Open Access
- 1 June 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 116 (6) , 1704-1710
- https://doi.org/10.4049/jimmunol.116.6.1704
Abstract
An analysis of the typing results of a 70-member chronic lymphatic leukemia B cell panel revealed evidence for 13 possible groups of the Merrit alloantigenic system. Six of these appeared possibly allelic and may represent a segregant series. The CLL panel was also fully typed for HLA and some degree of linkage dysequilibrium between Merrit and HLA seemed apparent from the data. Merrit antibodies can be absorbed out with selected surface membrane immunoglobulin (SMIG)-positive normal lymphocytes and less so or not at all with E rosette-forming T cells or Fc-positive SMIG-negative lymphocytesThis publication has 1 reference indexed in Scilit:
- Cytotoxicity Test with Frozen LymphocytesInternational Archives of Allergy and Immunology, 1966