EXPERIMENTAL BOVINE TRYPANOSOMIASIS CHANGES IN CATABOLISM OF SERUM IMMUNOGLOBULINS AND COMPLEMENT COMPONENTS IN INFECTED CATTLE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 35  (5) , 811-816
Abstract
The turnover of serum proteins of calves experimentally infected with Trypanosoma congolense was compared to that of normal uninfected cattle. All proteins examined had much increased catabolic rates in infected animals. In normal animals the average half-lives in days for each protein were the following: Ig[immunoglobulin]G1 17.4, IgG2 22.4, IgM 4.8, IgA 3.4, IgE 1.9, C1 [complement component 1] 5.6 and C3 2.9. In trypanosome infected cattle the average half-lives were IgG1 1.9, IgG2 1.7, IgM 0.9, IgA 1.2, IgE 0.9, C1 1.2 and C3 1.1 days.