Antibiotic Treatment of Rhinitis and Sinusitis

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Abstract
The most common organisms causing bacterial sinusitis are pneumococci and Haemophilus influenzae. Accordingly, in a patient not allergic to penicillin, ampicillin or amoxicillin appears to be the antibiotic of choice in empirical treatment of bacterial sinusitis. In penicillin-allergic patients, or in areas with a high incidence of β-lactamase-producing H. influenzae, co-trimoxazole would probably be a better choice. Organisms obtained by culture of nasal secretions do not correlate well with organisms obtained from sinuses by direct puncture aspiration. Therefore, culture of nasal secretions is not recommended.

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