Experimental Osteoporosis and Parathyroid Activity

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Abstract
Adult cats fed a low-Ca diet developed osteoporosis. Control cats fed this same diet with added Ca or cats with their parathyroids removed did not develop osteoporosis. The serum Ca and P values in the low-Ca group were lower than in the controls, suggesting that the dietary Ca deficiency causes a decrease of the serum Ca level which stimulates the parathyroids, thus increasing bone resorption and producing osteoporosis. The bone changes are described and related to parathyroid activity and osteomalacia.

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