High resolution bone mineral densitometry with a gamma camera

Abstract
A technique is described by which the regional distribution of bone mineral can be determined in bone samples from small animals. The technique employs an Anger camera interfaced to a medical computer. High resolution (<1 mm) imaging is possible by producing magnified images of the bone samples. Regional densitometry of femurs from oophorectomised and bone grafted rats demonstrated significant heterogeneity of bone mineral loss.