The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: Free radical formation and NAD(P)H: Quinone-acceptor oxidoreductase (DT-diaphorase) activity
- 31 December 1991
- journal article
- Published by Elsevier in Free Radical Biology & Medicine
- Vol. 10 (6) , 359-370
- https://doi.org/10.1016/0891-5849(91)90044-4
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Mechanism(s) of bioreductive activation: The example of diaziquinone (AZQ)Free Radical Biology & Medicine, 1989
- Caffeine, aminoimidazolecarboxamide and dicoumarol, inhibitors of NAD(P)H dehydrogenase (quinone) (DT diaphorase), prevent both the cytotoxicity and DNA interstrand crosslinking produced by 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) in walker cellsBiochemical Pharmacology, 1989
- DT-diaphorase-catalysed reduction of 1,4-naphthoquinone derivatives and glutathionyl-quinone conjugates. Effect of substituents on autoxidation ratesBiochemical Journal, 1989
- DT-diaphorase-catalyzed two electron reduction of quinone epoxidesFree Radical Biology & Medicine, 1987
- Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of actionBiochemistry, 1987
- Overview of enzyme systems involved in bioreduction of drugs and in redox cyclingBiochemical Pharmacology, 1986
- Diaziquone given as a continuous infusion is an active agent for relapsed adult acute nonlymphocytic leukemiaBlood, 1986
- Mechanism for the Reductive Activation of DiaziquoneJournal of Pharmaceutical Sciences, 1985
- Treatment of patients with recurrent primary brain tumors with AZQNeurology, 1984
- [56] DT diaphorasePublished by Elsevier ,1967