Effects of 2-Nicotinamidoethyl Nitrate (SG-75) on Dog Coronary Artery and Cat Papillary Muscle
- 1 January 1979
- journal article
- research article
- Published by International Heart Journal (Japanese Heart Journal) in Japanese Heart Journal
- Vol. 20 (4) , 549-556
- https://doi.org/10.1536/ihj.20.549
Abstract
Effects of SG-75 on isolated dog coronary artery and cat papillary muscle were investigated. SG-75 dose dependently relaxed the isolated coronary arterial strips contracted with K. Large doses of SG-75 depressed contraction of papillary muscle driven with electrical stimulation and inhibited enhancement of contraction of papillary muscle induced by Ca and isoproterenol. SG-75 may have a weak Ca2+-antagonistic action.This publication has 4 references indexed in Scilit:
- Effect of 2-Nicotinamidethyl Nitrate (SG 75) on Coronary CirculationJapanese Heart Journal, 1978
- The Effect of Calcium and Beat Interval on the Contractile Force and Refractoriness of the Isolated Rat Atrium in the Absence and Presence of Nifedipine: A Possible Mechanism for the Negative Staircase PhenomenonActa Pharmacologica et Toxicologica, 1977
- Effects of Calcium-Antagonistic Coronary Vasodilators on Myocardial Contractility and Membrane PotentialsThe Japanese Journal of Pharmacology, 1977
- Effects of sodium nitroprusside and nitroglycerin on tension prolongation of cat papillary muscle during recovery from hypoxia.Circulation Research, 1976