Synthesis of a non-nucleoside reverse transcriptase inhibitor in the alkenyldiarylmethane (ADAM) series with optimized potency and therapeutic index

This publication has 12 references indexed in Scilit:

• What can be Expected from Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in the Treatment of Human Immunodeficiency Virus Type 1 (HIV-1) Infections?
  Reviews in Medical Virology, 1996
• Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: Strategies to overcome drug resistance development
  Medicinal Research Reviews, 1996
• Synthesis and Biological Evaluation of Certain Alkenyldiarylmethanes as Anti-HIV-1 Agents Which Act as Non-Nucleoside Reverse Transcriptase Inhibitors
  Journal of Medicinal Chemistry, 1996
• Synthesis and biological evaluation of an alkenyldiarylmethane (ADAM) which acts as a novel non-nucleoside HIV-1 reverse transcriptase inhibitor
  Bioorganic & Medicinal Chemistry Letters, 1995
• Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors
  Nature Structural & Molecular Biology, 1995
• Non-nucleoside inhibitors of HIV-1 reverse transcriptase: molecular modeling and x-ray structure investigations
  Journal of Medicinal Chemistry, 1993
• Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
  Science, 1992
• HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587
  Biochemical Pharmacology, 1992
• Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
  Nature, 1990
• Pheromone, XXXII. Bausteine zur Darstellung zweifach ungesättigter Schmetterlings‐pheromone
  European Journal of Organic Chemistry, 1981