Effect of human chorionic gonadotropin on growth velocity and biological growth parameters in adolescents with thalassaemia major
- 1 January 1989
- journal article
- research article
- Published by Springer Nature in European Journal of Pediatrics
- Vol. 148 (4) , 300-303
- https://doi.org/10.1007/bf00444118
Abstract
The effect of long-term human chorionic gonadotropin (HCG) therapy on the linear growth and biological growth parameters was studied in six thalassaemic boys aged 14.5–15.5 years old with hypogonadotropic hypogonadism. A significant (PPPPPP<0.001) lower than in normal prepubertal children. This study suggests that in thalassaemia major an impaired GH-RH release can be observed, in addition to the described alteration in Sm-C generation.Keywords
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