Organic azides in heterocyclic synthesis, 12. Thermal cyclization of 4‐azido‐3‐formyl‐2‐quinolones to isoxazolo[4,3‐c]quinolones
- 12 April 1991
- journal article
- research article
- Published by Wiley in European Journal of Organic Chemistry
- Vol. 1991 (4) , 401-403
- https://doi.org/10.1002/jlac.199119910174
Abstract
Thermolysis of the 4‐azido‐3‐formyl‐2‐quinolone 6, which was prepared from the 4‐hydroxy‐2‐quinolone 1, afforded the ringclosed isoxazoloquinolone 7. 3‐(Arylaminomethylene)‐2,4‐quinolinediones 2 could not be transformed into an azide precursor in order to obtain the corresponding pyrazoloquinolone but yielded by attempted chlorination either 5‐methyldibenzo[b,h][1,6]naphthyridine‐6(5H)‐one (9) or 4‐chloro‐3‐formyl‐1‐methyl‐2(1H)‐quinolone (5).Keywords
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