Polymorphonuclear neutrophil chemotaxis induced and inhibited by Bacteroides spp
- 1 September 1981
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 33 (3) , 806-810
- https://doi.org/10.1128/iai.33.3.806-810.1981
Abstract
A possible virulence factor for Bacteroides s.c. abscesses was found. The effect of Bacteroides culture filtrate and outer membrane on chemotaxis of rabbit peritoneal polymorphonuclear (PMN) neutrophils was assayed in Boyden chambers and via exocytosis of N-acetyl-.beta.-glucosaminidase. Both Bacteriodes culture filtrate and outer membrane elicited some chemotaxis, as measured in the Boyden chamber; however, they had little effect upon exocytosis in cytochalasin B-treated PMN neutrophils. In the presence of serum complement, they completely abolished PMN neutrophil movement in the Boyden chamber assay, yet they gave a definite positive response for the exocytosis assay in the presence of serum complement or activated complement fragment.This publication has 20 references indexed in Scilit:
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