Sustained Suppression of the Pituitary-Gonadal Axis by Leuprorelin Three-Month Depot Microspheres in Rats and Dogs
- 1 January 1994
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 11 (8) , 1199-1203
- https://doi.org/10.1023/a:1018905403359
Abstract
The pharmacological effects of leuprorelin three-month depot microspheres were investigated in rats and dogs. After s.c. and i.m. injection, the microspheres provided similar linear drug release and...Keywords
This publication has 7 references indexed in Scilit:
- Preparation of Three-Month Depot Injectable Microspheres of Leuprorelin Acetate Using Biodegradable PolymersPharmaceutical Research, 1994
- Sustained Pharmacological Activities in Rats Following Single and Repeated Administration of Once-a-Month Injectable Microspheres of Leuprolide AcetatePharmaceutical Research, 1991
- Pharmacokinetics of Once-a-Month Injectable Microspheres of Leuprolide AcetatePharmaceutical Research, 1991
- ONE-MONTH RELEASE INJECTABLE MICROCAPSULES OF A LUTEINIZING-HORMONE-RELEASING HORMONE AGONIST (LEUPROLIDE ACETATE) FOR TREATING EXPERIMENTAL ENDOMETRIOSIS IN RATS1988
- In vivo release profiles of leuprolide acetate from microcapsules prepared with polylactic acids or copoly(lactic/glycolic) acids and in vivo degradation of these polymers.CHEMICAL & PHARMACEUTICAL BULLETIN, 1988
- Long-acting delivery systems for peptides: inhibition of rat prostate tumors by controlled release of [D-Trp6]luteinizing hormone-releasing hormone from injectable microcapsules.Proceedings of the National Academy of Sciences, 1984
- Controlled Release of a Luteinizing Hormone-Releasing Hormone Analogue from Poly(d,l-lactide—co-glycolide) MicrospheresJournal of Pharmaceutical Sciences, 1984