Relationship between Pulmonary Embolism, Airway Obstruction and Hypersensitivity of the Airways in Dogs

Abstract
Experiments in dogs showed an increase in ▵Poes/100 ml TV after embolization which returns to normal after blocking the vagus nerves, indicating an increase in airway resistance. A marked sensitization to ACh inhalation by embolism with both blood clots and glass beads was demonstrated. This hypersensitivity is vagus-dependent.