Unsaturated steroids. Part I. Synthesis of 22,23-dihydroergosterol
- 1 January 1976
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 8,p. 826-828
- https://doi.org/10.1039/p19760000826
Abstract
Bromination of 5α-ergost-7-en-3-one furnishes a mixture of the 2- and 4-bromo-derivatives which is readily dehydrobrominated to yield the isomeric 5α-ergosta-1,7- and ergosta-4,7-dien-3-ones. Reduction of the enol acetate of ergosta-4,7-dien-3-one yields 22,23-dihydroergosterol. Some reactions of the 22,23-epoxide of ergosterol are reported; the configurational assignment of the 22-hydroxy-group in 3,22-dihydroxyergosterols has been clarified.This publication has 1 reference indexed in Scilit:
- Synthetic uses of steroidal ring B diene protection: 22,23-dihydroergosterolJournal of the Chemical Society, Perkin Transactions 1, 1976