Mutagenic and cell transforming activities of 1-Chlor-2,4-dinitrobenzene (DNCB) and squaric-acid-dibutylester (SADBE)
- 1 October 1980
- journal article
- research article
- Published by Springer Nature in Archives of Toxicology
- Vol. 45 (4) , 307-314
- https://doi.org/10.1007/bf00293811
Abstract
In the Salmonella/microsome test, DNCB was mutagenic for TA100, TA1538, and TA98, whereas SADBE did not induce mutations in the test system. The ability of the compounds to transform BHK cells being able to reproduce in semi-solid agar was investigated. DNCB induced a dose-dependent increase in transformed cells, SADBE did not show this effect.Keywords
This publication has 12 references indexed in Scilit:
- An evaluation of 6 short-term tests for detecting organic chemical carcinogensBritish Journal of Cancer, 1978
- [Alopecia areata: successful half-side treatment with DNCB].1977
- A method for detecting carcinogenic organic chemicals using mammalian cells in cultureBritish Journal of Cancer, 1977
- INDUCTION OF HAIR GROWTH IN ALOPECIA AREATA WITH D.N.C.B.The Lancet, 1977
- Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their useNature, 1976
- Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.Proceedings of the National Academy of Sciences, 1976
- Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.Proceedings of the National Academy of Sciences, 1975
- Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity testMutation Research/Environmental Mutagenesis and Related Subjects, 1975
- An Improved Bacterial Test System for the Detection and Classification of Mutagens and CarcinogensProceedings of the National Academy of Sciences, 1973
- Absorption of Some Organic Compounds Through the Skin in ManJournal of Investigative Dermatology, 1970