Measurement of plasma glycoside level following pengitoxin administration
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Pharmacology
- Vol. 13 (5) , 389-391
- https://doi.org/10.1007/bf00644614
Abstract
Summary 16-Acetyl-gitoxin, the cardioactive metabolite of pengitoxin, was estimated by the86Rb uptake technique. In 70 consecutive patients taking an oral maintenance dose of pengitoxin 0.4 mg (Pentagit®), the mean plasma concentration was 20.8±6.7 ng/ml. Toxic signs were not observed up to plasma levels of 40 ng per ml.Keywords
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