ELECTROGRAM OF ISOLATED PAPILLARY MUSCLE OF THE CAT HEART

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Abstract
Using papillary muscle from the right ventricle of the cat''s heart, the electrogram was recorded when the muscles were contracting vigorously spontaneously or upon stimulation and were well-oxygenated. This electrogram is monophasic having a fast negative component ("R") followed by a slow deflection in the same direction ("T"). Absolute anoxia (reduction in available O2) or relative anoxia (increased rate of stimulation) both cause inversion of the T deflection. Decreasing temp. prolongs R and T deflections (Q10 = 2) and increases the amplitude and duration of contractions. The effect of digitoxin, HgCl2 and sym-pathomimetic amines was found to be similar to the actions noted in the ecg.

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