Radiographic grading system for renal cell carcinoma with clinical and pathological correlation.

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Abstract
Clinical records, pathological specimens, and radiographs of 106 patients with renal cell carcinoma were reviewed and coded for computer analysis. Twenty radiographic features of the tumor were examined for their possible prognostic significance. Three angiographic signs were associated with an unfavorable prognosis: tumor size > 10 cm, poor definition of tumor margins, and parasitic circulation. A new radiological grading system was developed based on these signs. Upon comparison with existing clinical staging and pathological grading systems, the new system predicted prognosis equally well. In addition, it had the advantages of predicting prognosis preoperatively and being simple for clinical use.