Determination of colonization resistance of the digestive tract by biotyping of Enterobacteriaceae
- 1 October 1990
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 105 (2) , 355-361
- https://doi.org/10.1017/s0950268800047944
Abstract
SUMMARY In studies concerning the effect of antibiotics on faecal microflora, Colonization Resistance is an important parameter. Colonization Resistance correlates inversely with the number of different biotypes of Enterobacteriaceae isolated from faecal samples. Nine healthy volunteers were studied during 6 weeks, in order to determine the natural variation in the number of different biotypes of Enterobacteriaceae per faecal sample. The numbers of biotypes ranged from 1–15 per faecal sample, the mean number of biotypes varied between 2·6 and 7·3 different biotypes per faecal sample per healthy volunteer. Inter-individual variations of five biotypes in the mean number of biotypes per faecal sample are normal. We assessed the minimal number of faecal samples that should be taken for comprehensive biotyping so as to determine reliably the mean number of different biotypes representative for the Colonization Resistance of an individual. It was found that a minimum of four faecal samples was required.This publication has 13 references indexed in Scilit:
- A comparative study of the effect of oral treatment with augmentin, amoxycillin and bacampicillin on the faecal flora in miceZentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1988
- Bacterial Translocation and Gram-Negative Bacteremia in Patients with Hematological MalignanciesThe Journal of Infectious Diseases, 1985
- Relation between the faecal concentration of various potentially pathogenic microorganisms and infections in individuals (mice) with severely decreased resistance to infectionAntonie van Leeuwenhoek, 1978
- Infection in Acute Leukemia Patients Receiving Oral Nonabsorbable AntibioticsAntimicrobial Agents and Chemotherapy, 1978
- Infection by and distribution of biotypes of Enterobacteriaceae species in leukaemic patients treated under ward conditions and in units for protective isolation in seven hospitals in EuropeInfection, 1977
- Determination of the colonization resistance of the digestive tract of individual miceEpidemiology and Infection, 1974
- Biotyping of Enterobacteriaceae as a test for the evaluation of isolation systemsEpidemiology and Infection, 1972
- Origin of Infection in Acute Nonlymphocytic LeukemiaAnnals of Internal Medicine, 1972
- Colonization resistance of the digestive tract in conventional and antibiotic-treated miceEpidemiology and Infection, 1971