Effect of ranitidine, a new H2-antagonist, on gastric and pancreatic secretion in duodenal ulcer patients
- 1 October 1980
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 25 (10) , 737-743
- https://doi.org/10.1007/bf01345291
Abstract
The effects of a new H2-receptor blocker, ranitidine, given intravenously (for comparison with cimetidine) or orally on gastric and pancreatic secretion have been studied in duodenal ulcer patients. Ranitidine appears to be several times more potent and a longer-acting inhibitor of gastric secretion than cimetidine. This H2 blocker does not affect pancreatic bicarbonate and enzyme secretion.Keywords
This publication has 24 references indexed in Scilit:
- Comparison of ranitidine and cimetidine in the inhibition of histamine, sham-feeding, and meal-induced gastric secretion in duodenal ulcer patients.Gut, 1980
- INHIBITION OF PENTAGASTRIN-STIMULATED AND NOCTURNAL GASTRIC SECRETION BY RANITIDINEThe Lancet, 1979
- GASTRIC INHIBITORY ACTION OF H2-ANTAGONISTS RANITIDINE AND CIMETIDINEThe Lancet, 1979
- CIMETIDINE, AN H2-ANTIHISTAMINE, STIMULATES PROLACTIN SECRETION IN MANJournal of Clinical Endocrinology & Metabolism, 1977
- GYNÆCOMASTIA WITH CIMETIDINEThe Lancet, 1977
- Effect of metiamide on the response to secretin and cholecystokinin in man.Gut, 1975
- The pathophysiology of duodenal ulceration.Gut, 1974
- Definition and Antagonism of Histamine H2-receptorsNature, 1972
- A spectrophotometric determination of trypsin and chymotrypsinBiochimica et Biophysica Acta, 1955
- THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBINThe Journal of general physiology, 1938