NMR chemical shift imaging in three dimensions.
- 1 June 1982
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 79 (11) , 3523-3526
- https://doi.org/10.1073/pnas.79.11.3523
Abstract
A method for obtaining the 3-dimensional distribution of chemical shifts in a spatially inhomogeneous sample using Fourier transform NMR is presented. The method uses a sequence of pulsed field gradients to measure the Fourier transform of the desired distribution on a rectangular grid in (k,t) space. Simple Fourier inversion then recovers the original distribution. An estimated signal/noise ratio of 20 in 10 min is obtained for an image of the distribution of a 10 mM phosphorylated metabolite in the human head at a field of 20 kG [kilogauss] with 2 cm resolution.This publication has 5 references indexed in Scilit:
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