Interleukin 2, interleukin 2 receptor, and interferon-γ synthesis and mRNA expression in phorbol myristate acetate and calcium lonophore A23187-stimulated T cells from elderly humans

This publication has 33 references indexed in Scilit:

• Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors.
  Journal of Clinical Investigation, 1988
• Phytohemagglutinin induced proliferation by aged lymphocytes: Reduced expression of high affinity interleukin-2 receptors and interleukin-2 secretion
  Life Sciences, 1988
• Diminished calcium influx in lectin‐stimulated T cells from old mice
  Journal of Cellular Physiology, 1987
• Activation of protein kinase C down-regulates IFN-gamma receptors
  Biochemical and Biophysical Research Communications, 1987
• Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified tac-positive T cells
  Mechanisms of Ageing and Development, 1986
• Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes
  Cell, 1986
• Decline, with age, in the proportion of mouse T cells that express IL-2 receptors after mitogen stimulation
  Mechanisms of Ageing and Development, 1986
• Molecular cloning and expression of cDNAs for the human interleukin-2 receptor
  Nature, 1984
• Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans.
  Journal of Clinical Investigation, 1981
• Interferons and the immune system
  Nature, 1980