Induction of rat hepatic UDP-glucuronosyltransferases by dietary ethoxyquin
- 1 January 1980
- journal article
- research article
- Published by Springer Nature in Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie
- Vol. 310 (3) , 249-252
- https://doi.org/10.1007/bf00499919
Abstract
Dietary administration of 0.5% ethoxyquin markedly enhanced rat hepatic UDP-glucuronosyltransferase activities. Both 3-methylcholanthrene- and phenobarbital-inducible glucuronidation reactions were stimulated by the antioxidant. In contrast, phenobarbital-inducible bilirubin glucuronidation was not affected by ethoxyquin.This publication has 11 references indexed in Scilit:
- Purification of Rat‐Liver Microsomal UDP‐glucuronyltransferaseEuropean Journal of Biochemistry, 1979
- Effect of 2(3)-tert-butyl-4-hydroxyanisole administration on the activities of several hepatic microsomal and cytoplasmic enzymes in miceBiochemical Pharmacology, 1979
- Induction of rat hepatic epoxide hydratase by dietary antioxidantsToxicology and Applied Pharmacology, 1979
- Ethoxyquin feeding to rats increases liver microsome-catalyzed formation of benzo(a)pyrene diol epoxide — DNA adductBiochemical and Biophysical Research Communications, 1978
- Demonstration of functional heterogeneity of hepatic uridine diphosphate glucuronosyltransferase activities after administration of 3-methylcholanthrene and phenobarbital to ratsBiochemical Journal, 1978
- ELEVATION OF HEPATIC GLUTATHIONE S-TRANSFERASE ACTIVITIES AND PROTECTION AGAINST MUTAGENIC METABOLITES OF BENZO(A)PYRENE BY DIETARY ANTIOXIDANTS1978
- Control of UDP-glucuronyltransferase activityBiochemical Pharmacology, 1975
- Reversibility of hepatic changes caused by ethoxyquinBiochemical Pharmacology, 1974
- Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferaseBiochimica et Biophysica Acta (BBA) - Enzymology, 1973
- Inhibition of Carcinogenic and Toxic Effects of Polycyclic Hydrocarbons by Phenolic Anti-oxidants and Ethoxyquin2JNCI Journal of the National Cancer Institute, 1972