The Effects of Protoveratrine on Plasma Potassium Levels in The Cat and Rabbit
- 1 December 1959
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 11 (Supplement) , 185T-194T
- https://doi.org/10.1111/j.2042-7158.1959.tb10430.x
Abstract
Protoveratrine has been shown to increase the level of venous plasma potassium (K+) in intact rabbits and anaesthetised cats. By the use of restricted circulation experiments it has been demonstrated that at therapeutic dose levels protoveratrine causes an increase in the level of K+ in the plasma of blood from the coronary circulation but not from skeletal muscle. The possible significance of this finding and its relation to the Bezold-Jarisch reflex is discussed.Keywords
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