THE TEMPORARY CONTROL OF POST-OPERATIVE TETANY IN THYRO-PARATHYROIDECTOMIZED DOGS BY THE ADMINISTRATION OF THYROID HORMONE

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Abstract
In approximately 55% of a series of 31 dogs, tetany following thyro-parathyroidectomy was temporarily controlled by experimental hyperthyroidism. The remaining 45% died as in uncontrolled tetany. Experimental hyperthyroidism maintained the serum Ca above the tetany level for 1-3 wks. in 55% of a series of 31 thyro-parathyroidectomized dogs. In all thyro-parathy-roidectomized dogs of this series, a further decrease in the serum Ca followed the discontinuance of thyroid ingestion. In the unoperated animals, moderately severe hyperthyroidism, experimentally induced, causes an elevation in the level of the acid soluble P of the blood serum which may reach 100% above normal, with no change in the serum Ca. After thyro-parathyroidectomy, the increased concentration of the blood P persists, or shows a tendency to a still higher elevation with increased severity of the hyperthyroidism, regardless of the decrease in the serum Ca.

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