INTERACTION OF METAL-IONS WITH NUCLEIC-ACIDS - INTERACTION OF COPPER(II) WITH PYRIMIDINE NUCLEOSIDES AND THEIR DERIVATIVES
- 1 January 1979
- journal article
- research article
- Vol. 26 (3) , 249-266
Abstract
In aqueous and non-aqueous solutions, Cu(II) interacts with the N-3 of cytidine but not with the carbonyl group O of pyrimidine nucleosides. In aqueous solution, Cu(II) interacts with the phosphate group and ribose of pyrimidine nucleotides, and additionally with N-3 of 5''-CMP. Broadening of NMR signals of the H-5 proton of 5''-UMP and C-5 of 5''-UMP and 5''-TMP results probably from the interaction between metal ion and the phosphate group situated in direct vicinity of the above atoms. In the Cu(II)-pyrimidine nucleotide complexes in solid state, Cu is coordinated with the phosphate group, and in 5''-CMP additionally with the pyrimidine moiety of the nucleotide.This publication has 6 references indexed in Scilit:
- INTERACTION OF METAL-IONS WITH NUCLEIC-ACIDS - INTERACTION OF COPPER(II) WITH GUANOSINE AND ITS DERIVATIVES1978
- INTERACTION OF METAL-IONS WITH NUCLEIC-ACIDS - INTERACTION OF COPPER(II) WITH INOSINE AND ITS DERIVATIVES1978
- X-ray structure of a compound of cobalt with uridine 5′-monophosphate Evidence for metal-phosphate bonding onlyBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1977
- X-Ray crystal structure of a stable metal–5′-uridine monophosphate (UMP) complex, [Cu(5′-UMP)(2,2′-dipyridylamine)(H2O)]2Journal of the Chemical Society, Chemical Communications, 1977
- The crystal and molecular structure of the polymeric complex of zinc(II) with cytosine 5′-phosphate: Metal bonding to both N(3) and phosphateBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976
- Interactions of Metal Ions with Polynucleotides and Related Compounds. VII. The Binding of Copper(II) to Nucleosides, Nucleotides, and Deoxyribonucleic Acids*Biochemistry, 1966