Diastereoselective Ruthenium−Cp Complexation of Enantiopure Arene Compounds Possessing Stereogenic Benzylic Alcohol Functionalities

Abstract
Enantiopure (arene)ruthenium compounds possessing a stereogenic benzylic alcohol functionality were stereoselectively synthesized by diastereoselective ruthenium−Cp complexation to a distinct arene face. This diastereoselective ruthenium−Cp complexation was further extended to biaryl compounds linked with a six-membered lactone bridge for the synthesis of enantiomerically pure, axially chiral biaryls.