Analysis of fresh frozen plasma administration with suggestions for ways to reduce usage

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Abstract
A programme for the daily monitoring of Fresh Frozen Plasma (FFP) usage, combined with continuous education in the correct use of FFP, was started at William Beaumont Hospital in 1985. In 2 years, this had resulted in a 77% reduction in FFP usage. An analysis of the type of cases which received FFP, after the major reduction had occurred, from July, 1985 through June, 1989 is presented. During this time 2,612 units were administered to 873 patients, an average of 54 units per month. According to the accepted criteria established by the Hospital Transfusion Committee, 67% of the transfused units on the medical service were deemed indicated, compared with 54% on the surgical service. Most of the FFP was used to treat patients with liver disease, or receiving coumadin, or undergoing coronary bypass surgery. Conditions which will decrease the need for FFP administration are also presented for consideration. The results indicate that a consistent monitoring and education programme can keep blood and blood component usage at a defensible minimum.