Catechol‐O‐Methyl Transferase and Monoamine Oxidase Activity in Some Tissues of the Bull

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Abstract
The catechol‐O‐methyl transferase activity in the retractor penis muscle, liver, and kidney of the bull was determined by measuring the amount of metanephrine formed from adrenaline when S‐adenosylmethionine was used as methyl donor. The monoamine oxidase activity in the same tissues was estimated By measuring the rate of disappearance of 5‐hydroxytryptamine added to the incubation mixture. There was a very low, if any, catechol‐O‐methyl transferase activity in the retractor muscle, a slight but distinct activity in the kidney, and a high one in the liver. The monoamine oxidase activity exhibited By the retractor muscle was moderate. In the liver the activity of this enzyme was high but it was still clearly exceeded by that in the kidney. The role of both enzymes in the function of the retractor muscle is briefly discussed.