Drug-Induced Deafness

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Abstract
Thirty-two of 11,526 medical inpatients (three per 1,000) monitored by the Boston Collaborative Drug Surveillance Program developed deafness of varying severity attributed to drugs administered while in the hospital. Drugs implicated in the development of deafness were aspirin (11 per 1,000 exposed), the aminoglycoside antibiotics (13 per 1,000 exposed), ethacrynic acid when given by the intravenous route (seven per 1,000 exposed), and quinidine (three per 1,000 exposed).

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