Localization of genes encoding apolipoproteins CI, CII, and E to the p13?cen region of human chromosome 19
- 1 October 1985
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 71 (2) , 144-146
- https://doi.org/10.1007/bf00283370
Abstract
The genes encoding apolipoproteins CI, CII, and E have been previously localized to chromosome 19. By use of rodent-human hybrid cell lines containing translocations of chromosome 19 we have now mapped these three genes to the region 19p13–19q13 and most probably 19p13–19 cen. The clustering of APOC1, APOC2, and APOE must reflect their common evolutionary background and suggests that they may be coordinately regulated. Polymorphisms detected for any one gene will be useful for inheritance studies of all three.Keywords
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