Protection of Mice from Lethal Infection with Aujeszky's Disease Virus by Immunization with Purified gVI
- 1 June 1988
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 69 (6) , 1411-1414
- https://doi.org/10.1099/0022-1317-69-6-1411
Abstract
Summary Virus envelope glycoprotein gVI (gp50) of Aujeszky's disease virus (ADV) was purified from a Nonidet P40-solubilized lysate of ADV-infected Vero cells by immunoaffinity chromatography using a monoclonal antibody against gVI. Mice immunized by the purified gVI produced virus-neutralizing antibody and were successfully protected against subsequent challenge with ADV.Keywords
This publication has 13 references indexed in Scilit:
- Humoral immune response to herpes simplex virus type 2 glycoproteins in patients receiving a glycoprotein subunit vaccineJournal of Virology, 1985
- Purification of Herpes Simplex Virus Glycoproteins B and C Using Monoclonal Antibodies and Their Ability to Protect Mice against Lethal ChallengeJournal of General Virology, 1985
- Characterization of the envelope proteins of pseudorabies virusJournal of Virology, 1984
- Isolation, characterization, and physical mapping of a pseudorabies virus mutant containing antigenically altered gp50Journal of Virology, 1984
- Immunogenicity of herpes simplex virus glycoproteins gC and gB and their role in protective immunityJournal of Virology, 1984
- Cell-mediated immunity to herpes simplex virus: specificity of cytotoxic T cellsInfection and Immunity, 1980
- Mutant analysis of herpes simplex virus-induced cell surface antigens: resistance to complement-mediated immune cytolysisJournal of Virology, 1980
- Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of Sciences, 1979
- Evidence for a ninth influenza viral polypeptideVirology, 1978
- Type-Common CP-1 Antigen of Herpes Simplex Virus Is Associated with a 59,000-Molecular-Weight Envelope GlycoproteinJournal of Virology, 1978