Therapy with a New Sulfonamide Triple Mixture: Sulfadiazine- Sulfamerazine-Elkosin

Abstract
The clinical use of a new sulfapyrimidine triple mixture in 127 adult patients with acute infections is reported. This mixture consists of equal amounts of elkosin, sulfamerazine and sulfadiazine. Elkosin replaces the isomer sulfamethazine, a commonly used third component. The latter is less soluble and subject to substantially higher in vivo conjugation. Therapeutic results and toxic reactions are presented in tables.