ELECTRO-ENCEPHALOGRAPHIC PATTERNS IN EXPERIMENTAL EPILEPSY*

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Abstract
In monkeys in which chron-ic recurrent epilepsy was produced by the application of alumina cream to the motor cortex of one side of the brain, the following typical Eeg. patterns were observed: Unilateral focus, consisting of irregular random and serial slow activity, spike potentials and variants of spike and dome formations; and bilateral abnormalities showing the above features on both sides of the brain. Subconvulsive doses of metrazol increased the focal discharges where the abnormality was minimal or moderate, but did not appreciably influence abnormalities which were already marked.

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