Antiinflammatory principle of Ephedra herbs.

Abstract
Since the traditional usage of an Oriental medicine mao, consisting of Ephedra herbs, suggests that it may possess antiinflammatory activity, a crude drug preparation, the aerial part of E. intermedia, was subjected to bioassay for antiinflammatory activity by 2 methods. The methanol extract was active. The extract was fractionated in monitoring the antiinflammatory activity, resulting in the isolation of (+)-pseudoephedrine as the active principle. The antiinflammatory effects of ephedrine analogs were determined by 4 assay methods; pseudoephedrine exhibited the strongest activity in the Whittle method, the carrageenan paw edema method in mice and the fertile egg method.

This publication has 3 references indexed in Scilit: