Dopamine Uptake and Release: Effects of Imipramine on the Pedal Ganglion of a Freshwater Pelecypod (Quadrula Pustulosa)
- 1 January 1973
- journal article
- research article
- Published by Taylor & Francis in International Journal of Neuroscience
- Vol. 5 (5) , 231-234
- https://doi.org/10.3109/00207457309149480
Abstract
1) Exposure of pedal ganglia to the tricyclic antidepressant imipramine lowered the total endogenous dopamine concentration by 27 %. 2) Field-stimulation of pedal ganglia labelled with 3H-dopamine caused release of the amine. 3) Release of 3H-dopamine from field-stimulated pedal ganglia may be potentiated by imipramine. 4) Newly accumulated 3H-dopamine mixes with the unlabeled endogenous dopamine in the ganglion and is not preferentially released.Keywords
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