Immunoglobulin Production by Human Lymphocytoid Lines and Clones: Absence of Genic Exclusion
- 23 April 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 172 (3981) , 382-383
- https://doi.org/10.1126/science.172.3981.382
Abstract
Immunoglobulin production was studied in established lines of normal human lymphocytes. Three lines which produced both immunoglobulin G and immunoglobulin M were cloned. Among the 25 immunoglobulin-producing clones, 23 produced both classes of immunoglobulins. These findings suggest that the phenomenon of genic exclusion does not hold for immunoglobulin production in lymphocytoid cells in culture.Keywords
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