Mucociliary Clearance in the Canine Lung during and after General Anesthesia

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Abstract
Central and peripheral pulmonary mucociliary clearance was assessed by tantalum bronchography and serial chest roentgenograms in dogs. Thiopental, 25 mg/kg, did not change clearance from awake values. Halothane, 1.2 MAC [minimum anesthetic concentration], for 6 h, delayed both central and peripheral clearance by at least 3 h. After halothane or diethyl ether, 1.2 MAC, for 2 h, recovery of mucociliary clearance was delayed for approximately 31/2 h.