Interferon immunosuppression: mediation by a suppressor factor
- 1 August 1980
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 29 (2) , 301-305
- https://doi.org/10.1128/iai.29.2.301-305.1980
Abstract
Suppression of the in vitro antibody response to sheep erythrocytes by mouse fibroblast interferon occurred by induction of suppressor cell activity in spleen cells. The suppressor cells produced a soluble factor which mediated the immunosuppression. The suppressor factor did not inhibit virus replication; thus, interferon probably regulates the B-cell response by a mechanism that is different from its antiviral effect.This publication has 16 references indexed in Scilit:
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