Free fatty acids in the pancreatitic arthritis syndrome
- 1 February 1983
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 26 (2) , 127-132
- https://doi.org/10.1002/art.1780260202
Abstract
Fat necrosis and arthritis occur in some individuals with pancreatitis. The intraarticular free fatty acid concentration was found to be markedly elevated in 2 patients with this pancreatitic arthritis syndrome. Injection of free fatty acids into rabbit knees reproduced the inflammatory synovial response including intracellular fat globules within leukocytes. Free fatty acids exceeding the available binding sites of albumin appear to mediate the extrapancreatic inflammatory manifestations of this syndrome.This publication has 25 references indexed in Scilit:
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