Improvement of pharmacokinetic, immunological and stability properties of asparaginase by conjugation to linear and branched monomethoxy poly( ethylene glycol)
- 1 July 1996
- journal article
- Published by Elsevier in Journal of Controlled Release
- Vol. 40 (3) , 199-209
- https://doi.org/10.1016/0168-3659(95)00185-9
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Biomedical and biotechnological applications of PEG- and PM-modified proteinsTrends in Biotechnology, 1995
- A Branched Monomethoxypoly(ethylene glycol) for Protein ModificationBioconjugate Chemistry, 1995
- Stabilization of L-Asparaginase Modified with Comb-Shaped Poly(ethylene glycol) Derivatives, in vivo and in vitroBioconjugate Chemistry, 1994
- Active Site Protection of Proteolytic Enzymes by Poly(ethylene glycol) Surface ModificationJournal of Bioactive and Compatible Polymers, 1993
- Chemical modification of L-asparaginase with a comb-shaped copolymer of polyethylene glycol derivative and maleic anhydrideBiochemical and Biophysical Research Communications, 1992
- Polyethylene Glycol Modified Trypsin Kinetics in Buffer and in Benzene: Dipeptide SynthesisBiocatalysis, 1991
- Anaphylaxis to L-Asparaginase during Treatment for Acute Lymphoblastic Leukemia in Children—Evidence of a Complement-Mediated MechanismPediatric Research, 1985
- Immunological Studies on Modified EnzymesInternational Archives of Allergy and Immunology, 1981
- Modification of E. coli L-asparaginase with polyethylene glycol: Disappearance of binding ability to anti-asparaginase serumBiochemical and Biophysical Research Communications, 1978
- L-Asparaginase Activity in Human and Animal SeraNature, 1968