BLADDER RESPONSE TO KLEBSIELLA INFECTION - SCANNING ELECTRON-MICROSCOPY STUDY
- 1 January 1977
- journal article
- research article
- Vol. 15 (3) , 227-231
Abstract
The early response of rat bladder epithelium to K. pneumoniae was examined using scanning electron microscopy. Increased bacterial adherence with time after challenge paralleled occurrence of strand formation and ulceration on the bladder epithelium. Early bladder response to the bacteria consisted of altered epithelial membrane structure, strand formation and exfoliation of some epithelial cells. K. pneumoniae apparently causes alterations in the bladder epithelium which may trigger an intrinsic bladder defense mechanism consisting of strand entrapment of bacteria, epithelial cell exfoliation and elimination of attached bacteria via voiding.This publication has 4 references indexed in Scilit:
- The Antibacterial Effect of the Bladder Surface: An Electron Microscopic StudyJournal of Urology, 1976
- Preservation of gastrointestinal bacteria and their microenvironmental associations in rats by freezingApplied and Environmental Microbiology, 1976
- SCANNING ELECTRON-MICROSCOPIC OBSERVATIONS OF COMMON CAROTID-ARTERY OF RAT .3. HEPARIN EFFECT ON PLATELETS1976
- Experiments with Induced Bacteriuria, Vesical Emptying and Bacterial Growth on the Mechanism of Bladder Defense to InfectionJournal of Urology, 1961