Noninvasive measurement of cardiac output using partial CO/sub 2/ rebreathing
- 1 January 1988
- journal article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Transactions on Biomedical Engineering
- Vol. 35 (9) , 653-661
- https://doi.org/10.1109/10.7266
Abstract
A noninvasive algorithm for estimating cardiac output is discussed. The technique is based on a differential form of the CO/sub 2/ Fick equation applied during normal ventilation and a 30-s period of partial rebreathing using additional deadspace. Using the Fick equation in a differential form eliminates the need to estimate mixed venous pCO/sub 2/, also the sensitivity of the cardiac output estimate to changes in the alveolar deadspace fraction is greatly reduced. The procedure is fully automated, requires minimal staff supervision, and provides cardiac output estimates every 3 1/2-min. Estimates of cardiac output when compared to thermodilution yielded a correlation coefficient of 0.92 with a linear regression slope of 0.92 (n=451). Temporary increases in alveolar deadspace did not significantly alter this relationship. Cardiac output estimates obtained during period of increased pulmonary shunt due to oleic acid infusion yielded a correlation coefficient of 0.90 with a linear regression slope of 0.92 when compared to direct thermodilution measurements.<>Keywords
This publication has 24 references indexed in Scilit:
- End-tidal CO2 as a guide to successful cardiopulmonary resuscitationCritical Care Medicine, 1985
- A feedback controller for ventilatory therapyAnnals of Biomedical Engineering, 1985
- Cardiac output determined by the CO2 rebreathing method with correction of lung-bag volume shrinkage.The Japanese Journal of Physiology, 1984
- The Reliability of the Carbon Dioxide-Rebreathing, Indirect Fick Method of Cardiac Output Determination in Patients with Pulmonary DiseaseClinical Science, 1983
- Determination of cardiac output based on breath-holdingCritical Care Medicine, 1980
- A new method for noninvasive bedside determination of pulmonary blood flowMedical & Biological Engineering & Computing, 1980
- Estimation of Cardiac Output from the Rate of Change of Alveolar Carbon Dioxide Pressure during RebreathingClinical Science, 1980
- Evaluation of the CO2 rebreathing cardiac output method in seriously ill patients.Circulation, 1977
- Cardiac output determination by simple one-step rebreathing techniqueRespiration Physiology, 1976
- Determination of the Mixed Venous CO2Pressure with a Rebreathing Method Correction for Volume Changes of the Lung-Bag SystemActa Physiologica Scandinavica, 1965