Studies on transfer ribonucleic acids and related compounds. XXV. Synthesis of E. coli tRNAfMet 5'-terminal tetranucleotide C-G-C-Gp and its sequence analog U-G-C-Gp.
- 1 January 1979
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 27 (2) , 341-345
- https://doi.org/10.1248/cpb.27.341
Abstract
A tetranucleotide C-G-C-Gp (cytidylyl-(3''-5'')-guanylyl-(3''-5'')-cytidylyl-(3''-5'')-guanosine 3''-phosphate) was synthesized by condensation of (Bz)bzC(Bz)-ibG(Bz)p with C(Bz)-ibG(Bz)pNHC6H4S(O)CH3, using 2,4,6-triisopropylbenzenesulfonyl chloride. This sequence corresponds to the Escherichia coli tRNAfMet 5''-terminus. A base substituted analog U-G-C-Gp was also synthesized by a similar procedure to that used for C-G-C-Gp. These tetranucleotides were characterized by enzymic hydrolysis.This publication has 3 references indexed in Scilit:
- Studies on transfer ribonucleic acids and related compounds. 20. A new versatile ribooligonucleotide block with 2'-(o-nitrobenzyl) and 3'-phosphorodianilidate groups suitable for elongation of chains in the 3' and 5' directionsJournal of the American Chemical Society, 1978
- A new ribo-oligonucleotide block synthesized by phosphorylation with p-chlorophenyl N-phenylchlorophosphoramidateJournal of the Chemical Society, Chemical Communications, 1978
- Studies on transfer ribonucleic acids and related compounds. X. Synthesis of the yeast tyrosine tRNA 5'-terminal oligonucleotides.CHEMICAL & PHARMACEUTICAL BULLETIN, 1976