The Culture of Tissue Cells in Clots Formed from Purified Bovine Fibrinogen and Thrombin.

Abstract
Expts. using clots formed from purified and sterilized thrombin and fibrinogen fractions of bovine blood plasma showed these clots to be equal to those from whole chick plasma for the cultivation of such tissue cells as rat fibroblasts, rat myoblasts, Jensen rat sarcoma cells, and chick fibroblasts. The use of these prepns. has the advantage over whole chick plasma in that storage of the purified reagents is practical for several wks., and the prepns. are sterile.
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