Arrayed Primer Extension Resequencing of Mutations in the TP53 Tumor Suppressor Gene: Comparison with Denaturing HPLC and Direct Sequencing
Open Access
- 1 July 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 51 (7) , 1284-1287
- https://doi.org/10.1373/clinchem.2005.048348
Abstract
Mutations of TP53 (17p13.1; OMIM 191170; PubMed accession number X54156) are common in cancers and are typically missense within exons 4–9, impairing the capaciKeywords
Funding Information
- International Agency for Research on Cancer
- Wellcome Trust International Senior Research Grant (070191/Z/03/Z)
- EMER (0518)
- European Community (EC) FP6 funding
This publication has 17 references indexed in Scilit:
- Human Papillomavirus Type 16 and TP53 Mutation in Oral CancerCancer Research, 2004
- p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosisCancer Cell, 2003
- Evaluating the arrayed primer extension resequencing assay of TP53 tumor suppressor geneProceedings of the National Academy of Sciences, 2002
- Prognostic significance of p53 mutations in colon cancer at the population levelInternational Journal of Cancer, 2002
- Emerging molecular markers of cancerNature Reviews Cancer, 2002
- High-Throughput Methods for Detection of Genetic VariationBioTechniques, 2001
- Arrayed Primer Extension: Solid-Phase Four-Color DNA Resequencing and Mutation Detection TechnologyGenetic Testing, 2000
- p53 and Human Cancer: The First Ten Thousand MutationsPublished by Elsevier ,1999
- Resequencing and mutational analysis using oligonucleotide microarraysNature Genetics, 1999
- TP53 mutations and breast cancer prognosis: Particularly poor survival rates for cases with mutations in the zinc‐binding domainsGenes, Chromosomes and Cancer, 1995