Coffee and Pancreatic Cancer
- 28 August 1981
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 246 (9) , 957-961
- https://doi.org/10.1001/jama.1981.03320090019020
Abstract
THE RECENT report that coffee may cause pancreatic cancer1was presented in a pattern that has become distressingly familiar. The alleged carcinogen is a commonly used product. The report was given widespread publicity before the supporting evidence was available for appraisal by the scientific community, and the public received renewed fear and uncertainty about the cancerous hazards lurking in everyday life. The research on coffee and pancreatic cancer was done with the case-control technique that has regularly been used in epidemiologic circumstances where the more scientifically desirable forms2of clinical investigation—a randomized controlled trial or a suitably performed observational cohort study—are either impossible or unfeasible. In case-control studies, the investigators begin at the end, rather than at the beginning, of the cause-effect pathway. The cases are selected from persons in whom the target disease has already developed. The controls are selected from persons in whom that disease has notKeywords
This publication has 8 references indexed in Scilit:
- Bias in analytic researchPublished by Elsevier ,2004
- Methodologic problems and standards in case-control researchJournal of Chronic Diseases, 1979
- Methodologic standards and contradictory results in case-control researchThe American Journal of Medicine, 1979
- ASSURING THE QUALITY OF QUESTIONNAIRE DATA IN EPIDEMIOLOGIC RESEARCHAmerican Journal of Epidemiology, 1979
- A method of estimating risk for occupational factors using multiple data sources: the Newfoundland lip cancer study.American Journal of Public Health, 1977
- Prospective versus retrospective approach in the search for environmental causes of malformations.American Journal of Public Health and the Nations Health, 1967
- Statistics—Servant of All ScienceScience, 1955
- Observation and ExperimentNew England Journal of Medicine, 1953