Response of Starved Rats and Polycythemic Rats to Graded Doses of Erythropoietin.
- 1 January 1961
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 106 (1) , 127-130
- https://doi.org/10.3181/00379727-106-26259
Abstract
The response to graded doses of erythropoietin was tested in assay rats with erythropoiesis arrested by starvation or transfusion-induced polycythemia. Measurement of red cell Fe59 incorporation proved to be a more sensitive means of assessing erythropoiesis than did reticulocyte counting. The log dose-response relationship was linear within the range tested. Starved rats responded to erythropoietin in a manner similar to assay rats with erythropoiesis arrested by transfusion.Keywords
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