Abstract
A simple criterion for mirror symmetry breaking in a non-linear chemical system is presented. The selection effect of external asymmetric agents in the process of generation and amplification of biomolecular asymmetry is studied. It is pointed out that this effect will play an important role at bifurcation point, but when the asymmetry of a system has been amplified to a certain extent, a weak asymmetric agent will no longer be able to change the chirality of the system.