SEMISYNTHETIC β-LACTAM ANTIBIOTICS. II

Abstract
A number of penicillins were synthesized from the .alpha.-hydrazinoarylacetic acids via the activated chloride hydrochlorides or via the mixed anhydride of the corresponding N2-benzyloxycarbonyl derivatives. Three penicillins show good activity against gram-positive and gram-negative bacteria and enhanced penicillinase resistance in comparison with ampicillin.

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